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Sunday, June 30, 2013

glioblastoma symptoms and signs

glioblastoma end stage symptoms cancer

The etiology of glioblastoma

Glioblastoma multiforme or grade IV astrocytoma, is a highly malignant brain tumor. In most cases, the tumor occurs in men between the ages of 40 and 60 years. Arises from glial cells of the central nervous system, and perform support functions for dividing neurons. It is one of the most aggressive tumors, and simultaneously, the most common - about 1/5 of all primary intracerebral tumors.The cause of this tumor is not known. Theories about the harmful effects of electromagnetic fields in the form of mobile communication is not scientifically proven.
Risk factors for glioblastoma include:
  1. Age. Most cases occur in 40-60 years.
  2. Paul. Occurs more often in men.
  3. Pilocytic and fibrillary astrocytoma (I and II). Approximately 10% of gliosarkom astrocytic tumors develop from low-grade malignancy.
  4. Diseases that cause genetic disorders. For example, neurofibromatosis.
  5. External factors. Exposure to ionizing radiation and chemicals (polyvinyl chloride).

Symptoms of glioblastoma

Symptoms of a glioblastoma vary depending on the location of the tumor. The most common symptom is a headache that is associated with increased intracranial pressure. Other manifestations include hypertension, seizures, dizziness. In addition, patients complain of blurred vision, drowsiness, numbness in the limbs. Often glioblastoma can reach large volumes before symptoms appear.Other typical symptoms include progressive disorder of memory, changes in behavior and character, which are the consequence of the destruction of the frontal and temporal lobes of the brain.

Diagnosis of glioblastoma

The tumor may take various forms, in most cases, the image of its heterogeneous structure.In the construction of the image using the following methods:
  1. MRI with the contrast agent is the most accurate method in the diagnosis of glioblastoma.
  2. SPEKT (single photon emission computed tomography) and PET examination is used in the differential diagnosis of glioblastoma from other tumor types.
Because glioblastoma is heterogeneous structure, a single sample may show a low degree of malignancy, which is not relevant to the aggressiveness of the tumor, so the most reliable method of confirming the diagnosis is stereotactic biopsy followed by post-mortem analysis.

Treatment of glioblastoma

MG treatment is complicated not only by the high aggressiveness of the tumor, but also a number of its features, including the resistance of tumors to standard chemotherapy and radiation therapy, deep germination neoplasms, complicating its surgical excision. Most clinics Russia can not go beyond the standard therapy, so the patient will either refuse treatment or therapy would be extremely inefficient.In collaboration with neurosurgery, radiology clinics and other members of the IMC Kliniken Koeln, we provide patients a full range of modern methods of neurosurgery, radiation therapy, chemotherapy, and targeted and innovative types of immunotherapy. After treatment, the rehabilitation of the tumor. Read more about the features of the treatment of glioblastoma brain.

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2 comments:

  1. Kang Nurul ImanJanuary 3, 2016 at 5:05 PM

    Thank you very Steady info ... hopefully more successful.
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